Recent murine models may rise new treatment possibilities such as the following: phycocyanin (PC)—a pigment–protein complex found in cyanobacteria—exerts anti-inflammatory and antioxidant effects in experimental models of COPD by regulating heme oxygenase-1 (HO-1) and nicotinamide adenine dinucleotide phosphate (NADPH) dehydrogenase quinone 1 (NQO1) in lung tissue, and by reducing NADPH oxidase 2 (NOX2) expression in pulmonary macrophages, it helped alleviate oxidative stress and inflammation [197]. This evidence concerns the gene NQO1 and chronic obstructive pulmonary disease.