S100B and AIDS: A preliminary study assessing if exosomal extracellular vesicles and Nef-containing-exosomal extracellular vesicles detected in plasma and cerebrospinal fluid correlate with the neurocognitive status of aviremic people living with HIV/AIDS has shown that neurocognitive impairment status was associated with the exosomal extracellular vesicles cargo, concentration, and exosomal extracellular vesicles-Nef levels [10].