Although this inconsistency can only be resolved by future independent replication studies, we need to note two points here: first, this recent study [8] recorded Kir in the presence of 30 mM TEA, but it has been reported [13] that 25 mM TEA fully blocked the inward rectification or Kir in MSNs; second, the DA loss-induced D1-MSN high excitability recently reported [8] would lead to hyperkinesia, opposite to the fact that DA loss leads to hypokinesia. The gene discussed is MSN; the disease is Hypokinesia.