At the molecular level, the platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) axis are heavily implicated in both cancer biology and atherogenesis [18]. This evidence concerns the gene AKT1 and cancer.