Moreover, that study demonstrated a significant correlation between IL-10 positivity and lymph node metastasis; breast cancer patients with nodal metastases were more likely to have high IL-10 in their tumors than those without nodal spread (67% vs. 41%, p ≈ 0.04 in their cohort) [33]. This evidence concerns the gene IL10 and metastatic malignant neoplasm in the lymph nodes.