In vitiligo melanocytes, high frequency of somatic mtDNA variants correlates with lower ROS scavenging capacity, augmented release in the culture supernatants of interleukin 1-β (IL1-β), IL-18, interferon α and β (IFNα/β), C-X-C motif chemokine ligand 9 (CXCL9), and C-X-C motif chemokine ligand 10 (CXCL10), resulting in strong PBMC recruitment [63]. Here, CXCL10 is linked to vitiligo.