However, the robust activation of DNA repair mechanisms via 8-oxoguanine DNA glycosylase (hOgg1), apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1), and DNA polymerase β explains the absence of heightened solar sensitivity, photodamage, skin aging, or an increased incidence of sun-induced nonmelanoma skin cancer in vitiligo patients [62]. The gene discussed is APEX1; the disease is skin aging.