Third, although our GSEA suggests that TSPAN32 expression is inversely correlated with cell cycle gene expression (with significant enrichment of the “cell cycle progression: E2F targets” and “cell cycle progression: G2/M checkpoint” biological processes)—an observation that aligns with literature indicating that TSPAN32 promotes quiescence in immune cells [8,25]—definitive functional validation of TSPAN32 as a tumor suppressor in T-cell leukemia is still required. Here, TSPAN32 is linked to neoplasm.