IFNG and infection: For instance, the TRASP chimeric protein from T. cruzi formulated with polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethylcellulose (Poly-ICLC—Hiltonol) induces strong, long-lasting protection against parasite infection in mice and dogs, primarily via Cluster of Differentiation 8 (CD8+) T cells and interferon-gamma (IFN-γ) [17].