AURKA and breast carcinoma: In this study, it was shown that AURKA expression was decreased in the human TNBC breast cancer cell line MDA-MB-231treated with DOX and 2S-13, AURKA expression was increased in the 4T1 mouse TNBC breast cancer cell line treated with DOX, and AURKA expression was decreased in the 4T1 mouse TNBC breast cancer cell line treated with 2S-13.