SDHC and breast carcinoma: In basal breast cancer cases with a high WWOX/HIF1A ratio, pathways favouring oxidative phosphorylation (Complexes I–V: NDUFA/B/C/S/V, SDHC, COX, ATP6 family) were enriched, reducing reliance on glycolysis and limiting tumour proliferation (Figure 2 and Figure 4).