Furthermore, pathways involved in xenobiotic metabolism (GSTs, DHDH, AKR7A2, HSD11B1L, CYP1B1, UGTs), drug metabolism, nucleotide metabolism, and homologous recombination (RAD51) reflect the tumour’s ability to adapt to environmental stressors and resist therapy. The gene discussed is CYP1B1; the disease is neoplasm.