In the study by Du et al., CoQ10 supplementation in a mouse model of allergic asthma significantly reduced airway eosinophilia, type 2 cytokines, IgE, and histamine levels, while upregulating Nrf2 expression and antioxidant defense genes, thereby attenuating airway inflammation, mucus hypersecretion, and oxidative stress injury [103]. Here, NFE2L2 is linked to Increased total eosinophil count.