In summary, transcriptomic results, along with confirmatory western blots (Fig. 2d), indicate that HIV infection led to increased expression of the key quiescence markers KLF2, TOB1 and CDKN2B, along with the downregulation of proliferation markers such as CD25/IL-2RA, CD71/TFRC and MYC (Fig. 2c,d, see also Extended Data Fig. 3c). This evidence concerns the gene CDKN2B and HIV infectious disease.