Kogelman et al. [86] detected co-expression patterns among eQTLs, integrated with protein data, and detected several obesity candidate genes, such as ENPP1, CTSL, and ABHD12B. More recently, integrative analyses on multiple obesity and neuro-related phenotypes provided further gene lists that potentially affected relevant phenotypes jointly [61, 77]. This evidence concerns the gene CTSL and obesity due to melanocortin 4 receptor deficiency.