Clinical ADPKD panel testing via short-read WGS (PKD1, PKD2, GANAB, HNF1B, TSC1, TSC, OFD1, UMOD, PKHD1), and targeted sequencing and MLPA of HNF1B did not identify a genetic cause of his ADPKD. This evidence concerns the gene TSC1 and autosomal dominant polycystic kidney disease.