Alcohol consumption (FB17) aggravates psoriasis by stimulating keratinocyte proliferation, promoting pro-inflammatory cytokines (TNF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\alpha$$\end{document}, IL-6), and impairing liver function, reducing detoxification of inflammatory mediators6,47,48. The gene discussed is IL6; the disease is psoriasis.