A study revealed that neutrophils rapidly induce NF-κB pathway-related genes after exposure to Rhizopus oryzae hyphae, leading to the upregulation of numerous pro-inflammatory genes and Toll-like receptor 2 [50], enhanced antifungal activity [51], In this study, neutropenia for more than 10 days was identified as an independent predictor for OS infection by Mucor in patients with hematological diseases. Here, TLR2 is linked to neutropenia.