Histopathology was evaluated in lung sections from GM-CSF KO (Fig. 2A through C), NRG (Fig. 2D), NSG (Fig.2E), and SCID-Beige (Fig. 2F) miceat specific time points during acute (GM-CSF KO mice) and chronic (GM-CSF KO,NSG, NRG, and SCID-Beige mice) stages of infection. The gene discussed is CSF2; the disease is infection.