FOLH1 and neoplasm: However, it must be noted that the binding of [68Ga]Ga-PSMA-617 to human plasma proteins is much higher compared to its binding to mouse serum proteins (59% vs. 6%) which may have relevant implications for biodistribution in the mouse model, such as lower tumour accumulation, but of course also lower activity in the blood compared to the human situation (Umbricht et al. 2018).