Additionally, in obese patients IPA has been negatively correlated with BMI, hs-CRP, hs-IL-6, and it has been reported that could inhibit the accumulation of TG and lower blood lipid levels, markers of progression in HIV infection, this suggest that in future research it will be that in future research it could be promising to look for these associations in PLWHIV, especially in those patients with dyslipidemia and who experiencing weight gain after using ART, conditions associated with an increased risk of T2D [48,49,50]. This evidence concerns the gene CRP and type 2 diabetes mellitus.