ABCG2 and cancer: For example, functions related to protein digestion and absorption; phenylalanine, tyrosine, and tryptophan biosynthesis; central carbon metabolism in cancer; ATP-binding cassette (ABC) transporters; biosynthesis of various secondary metabolites-part 3; cholesterol metabolism; secondary bile acid biosynthesis; and taurine and hypotaurine metabolism were all significantly changed by EC at T15 (Figure S1a,b).