Ang-2 and Ang-1 levels were considerably greater and lower, respectively, in children with retinopathy (an indication of real CM) in Malawian pediatric CM [33], and high Ang-2 (cut-point ~3.9 ng/mL) was an independent predictor of death (adjusted OR = 7.9, p < 0.001) [34]. Here, ANGPT1 is linked to retinal disorder.