Additionally, although there was no statistical relevance in the outcomes of mortality, hospital stay, and development of SIRS, it did allow us to identify the reduction in an indirect factor associated with these outcomes and the pathophysiology of AP, such as the decrease in CRP levels at 48 h, which is a factor that reflects a lower activation of the inflammatory cascade, closely related to complications like pancreatic necrosis [40]. This evidence concerns the gene CRP and systemic inflammatory response syndrome.