In the comparison between healthy controls (G1) and PRD cases (G2 at TP0), four cytokine biomarkers showed statistically significant associations with disease status: IL-1β (β = 0.0067, p = 0.0108), IL-8 (β = 0.0062, p = 0.0087), IL-4 (β = −11.1641, p = 0.0118), and IL-10 (β = −3.5171, p = 0.0210). The gene discussed is IL4; the disease is X-linked retinal dysplasia.