We and others have reported on the soluble and cellular components of the peritoneal immune environment [1,14,15], and found significantly elevated proinflammatory mediators such as interleukin-6 (IL-6), interleukin-8 (IL-8), fibroblast growth factor 2 (FGF2), and monocyte chemoattractant protein-1 (MCP-1 or CCL2) in the peritoneal fluid of PC patients [1]. This evidence concerns the gene FGF2 and pachyonychia congenita.