IL1B and fibromyalgia: In fibromyalgia (FM), serum levels of pro-inflammatory cytokines such as interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-1 beta (IL-1β), and tumor necrosis factor-alpha (TNF-α) are frequently elevated, whereas concentrations of anti-inflammatory cytokines are typically reduced [9].