While our study could not definitively assess the potential haplo-insufficient tumor suppressor role of Dicer1 due to limitations in evaluating partial loss, the effects observed upon complete Dicer1 loss align well with Swahari hypothesis, which proposes that total loss of Dicer1 results in impaired DNA damage response, accumulation of genomic instability and cell death, compromising tumor survival. The gene discussed is DICER1; the disease is neoplasm.