DICER1 and cancer: Future studies should investigate different timings of Dicer1 inactivation as well as Dicer1 inactivation in additional PTC mouse models and in other in vivo cancer models, particularly those where Dicer1 expression is known to be dysregulated between tumors and normal tissues, to assess whether the effects observed in our study are consistent across different genetic backgrounds and to validate the relevance of our findings [71].