IL17A and endothelial dysfunction: Commonly analysed biomarkers potentially associated with ageing include IL-6, hs-CRP, VCAM-1, ICAM-1, and IL-17A [79,218,219,220] Additionally, evidence indicates a significant role for soluble selectins, such as sP-selectin, in endothelial dysfunction and the development of atherosclerosis, which may indirectly link them to cardiovascular ageing [46].