PON1 and psoriasis: In the serum of patients with psoriasis, higher levels of oxidant markers—including advanced glycation end products (AGEs) and advanced oxidation protein products (AOPPs)—and lower levels of antioxidant enzymes—including lecithin-cholesterol acyltransferase (LCAT), paraoxonase-1 (PON1), and ferric-reducing ability of plasma (FRAP)—are observed, confirming a link between chronic inflammation and oxidative damage [238].