GSR and Friedreich ataxia: Bolotta et al. [12], in a study on leukocytes from seven FRDA patients and seven HC using qPCR, found overexpression of thioredoxin reductase 1 (TXNRD1) and nuclear factor erythroid 2-like 2 (NRF2) genes in FRDA patients, while SOD1, SOD2, CAT, GPX1, and GSH S-reductase (GSR) gene expressions were similar in FRDA patients and HC.