SERPINE1 and cancer: Sub-cell type 2 features CC terms like “extracellular exosome” and “focal adhesion,” MF terms such as “cadherin binding” and “peptidase inhibitor activity,” and BP terms including “cell migration” and “plasminogen activation.” This profile indicates a stromal or cancer cell modulating adhesion and ECM dynamics via exosomes and protease inhibition (e.g. SERPINE1) [52, 53].