MLH1 and cancer: Besides, we tested at least one parent for 2 patients (patient 3 and patient 5 in Table 1, Figures 3 and 5) with DM (MUTYH PV and mutation in another cancer gene) and we verified that the former inherited the MUTYH mutation from her father and the CHEK 2 mutation from her mother, and the latter the MUTYH mutation from his mother and the MLH1 mutation from his father.