PTPN11 and Noonan syndrome: Table 1 shows the demographic and descriptive statistics. The genetic variants included in the RASopathies group are described in detail in the Supplement. Still, most are youth with the PTPN11 genetic variant causing Noonan syndrome (n=34) or the NF1 variant causing neurofibromatosis type 1 (NF1, n=18).