PPP2R2B and major depressive disorder: These included pain traits like multisite chronic pain (MAML3, DCC, OLFM4, ANAPC4) and dorsalgia (CAMKV, MAML3, BCL11A, DCC, DCAF5, CNNM2, RABGAP1L, ZKSCAN2, ANAPC4, ARHGAP15, DRD2, MDGA2, CELF4), sleep traits like insomnia (CAMKV, DCC, OLFM4, CNNM2, MVK, NUDT12), and canonical psychiatric disorders like depression (DCC, NUDT12) and schizophrenia (CNNM2, STK31, PPP2R2B).