Furthermore, the BH and SH groups have higher infiltration of anti-tumor immune cells including activated CD4+ T cells, activated CD8+ T cells, effector memory CD8+ T cells, immature B cells and activated DC cells than the BL patients in TCGA cohort (Fig. 6b), as evaluated at the transcriptional level, suggesting that differential anti-tumor immune responses might also contribute to superior capacity of RRS/TMB combination to stratify CC patients with distinct prognosis. Here, CD4 is linked to neoplasm.