M-CSF levels were markedly elevated in the GVHD group (1490.20 ± 1635.54) compared with both the DED (68.23 ± 100.38) and non-GVHD groups (445.18 ± 521.69), with p-values less than 0.001 in both comparisons. This evidence concerns the gene CSF1 and graft versus host disease.