IL4 and allergic disease: Evidence from the literature suggests its potential to treat conditions such as Alzheimer’s disease through NF-κB blockade, apoptosis inhibition and antioxidant activity (Andrade et al., 2018; Seo et al., 2018) in allergic rhinitis have shown that resveratrol can effectively relieve allergy symptoms and significantly reduce inflammatory markers associated with allergic rhinitis, including blood levels of IgE, IL-4, TNF-α and eosinophils (Lv et al., 2018; Zhang et al., 2020b).