Higher BMI (β=0.087, p<0.001), current smoking (β=0.300, p<0.001), diabetes diagnosis (β=0.173, p<0.01), and elevated HbA1c (β=0.114, p<0.001) were all significantly associated with higher CRP levels, underscoring their role as key drivers of systemic inflammation. This evidence concerns the gene CRP and diabetes mellitus.