Some of the highly upregulated genes are involved in cancer metastasis, including SPC 25 and AKT3 (G2M progression), CCL22 and CXCL8 (immunoregulatory and inflammation), KISS1 (metastasis suppression and gonadotrophin-releasing hormone secretion), WNT7A (embryogenesis and oncogenesis), and OXTR (parturition and lactation). This evidence concerns the gene KISS1 and cancer.