CXCR6 and malaria: To evaluate the clinical relevance of CXCR6+ CD127− Tr1 cells in malaria, we leveraged samples collected from individuals enrolled in the Malaria in Uganda Systems Biology and Computational Approaches (MUSICAL) Study, a longitudinal cohort study that incorporated active and passive case finding with regimented follow-up for episodes of symptomatic malaria and asymptomatic parasitemia (Table S1).