INS and type 1 diabetes mellitus: CD68+ cells represented 19.6±14.3%, 9.5±8.1%, 3.9±6.9%, and 1.9±4.5% of the total cells in the peri-islet regions of the type 1 diabetes ICI, type 1 diabetes insulin-deficient islets (IDI), Aab+, and non-diabetic groups, respectively (Fig. 2A).