Laboratory test abnormalities have been documented regarding activated partial thromboplastin time (aPTT), prothrombin time (PT), prothrombin activity, International Normalized Ratio (INR), fibrinogen consumption, fibrin degradation product increase, thrombocytopenia, along with anemia and leukocytosis (21, 22, 70–79). The gene discussed is F2; the disease is Increased total leukocyte count.