Additionally, after adjustment for age, sex, history of hypertension, and history of diabetes, TNF-β expression level was positively correlated with the number of CMBs in the deep (β = 0.314, 95% CI:2.989-39.461, P = 0.023) and lobar regions (β = 0.433, 95% CI:15.363-59.857, P = 0.001). Here, LTA is linked to diabetes mellitus.