CD69 and obesity due to melanocortin 4 receptor deficiency: Although mean TCR expression level (MFI) was not significantly modulated between individuals with or without obesity (Figure 4A), strong negative correlations were observed between TCR levels and both CD25 (Figures 4B, R2 = 0.507, p<0.001) and CD69 (Figures 4C, R2 = 0.395, p<0.001) expression.