Some single-cell RNA sequencing (scRNA-seq) studies have identified immune cells in the CSF of AD patients and the meninges of tauopathy models.7,23,24 Nevertheless, we could not analyze the migration of T cells from the CSF or meninges in FTY720-treated Tau Tg mice, leaving the exact migration pathway uncertain. The gene discussed is MAPT; the disease is Alzheimer disease.