FOXP3 and neoplasm: Regulatory T cells (Tregs), marked by Foxp3, facilitate tumor immune evasion by creating a immunosuppressive TME.[56] Following incubation with a PE‐labeled anti‐mouse Foxp3 antibody, we observed that the proportion of mFoxp3+ T cells was 1.82% in the EcNPAQ group compared to 4.34% in the NS group, indicating that immunosuppressive TME in an activated state (Figure 6D).