LRG1 and heart disorder: Previous studies reported that cats with CHF have significantly higher acute-phase proteins, such as leucine-rich alpha-2-glycoprotein 1, serum amyloid A (SAA) and ceruloplasmin, compared with healthy cats.32 However, little information is available on CBC-derived inflammatory markers in cats, and only one study has been published specifically on cats with heart disease, reporting a correlation of NLR with echocardiographic parameters and prognosis of feline HCM.25