SOAT1 and autoimmune disease: Our findings revealed significant enrichment in pathways associated with SLE and other autoimmune diseases, including: antigen processing and presentation; cytokine-cytokine receptor interaction; cytosolic DNA-sensing pathway; JAK-STAT signalling; leukocyte transendothelial migration; neutrophil extracellular trap formation; NOD-like receptor signalling pathway; rheumatoid arthritis; RIG-I-like receptor signalling pathway Toll-like receptor signalling; Th1 and Th2 cell differentiation; Th17 cell differentiation; and chemokine signalling pathway (Fig. 1F, Sup.