The results of Figure 9a–g indicated that protein expression of GRP78, PERK, p‐ERK1/2, ATF4, CHOP, ERO1, and ATF6 increased in HF‐Sed versus control (p < 0.01), while exercise training decreased protein expression of GRP78, PERK, p‐ERK1/2, ATF4, CHOP, ERO1, and ATF6 in HF‐HIT versus HF‐Sed (p < 0.05). The gene discussed is HSPA5; the disease is hydrops fetalis.