In allergy-related cytokines (Table 1), Fat only led to significant increases in multiple BALF cytokines, notably IL-4, IL-5, IL-6, IL-12, IL-13, IL-17, IL-33, TNF-α, and IFN-γ, compared to the normal chow group (NC) (all P < 0.05 or P < 0.01). This evidence concerns the gene IL4 and allergic disease.