We found that three of the 92 PD GWAS signals associated with increased PD risk in Europeans and Asians15,21,26, the LRRK2 variant p.G2019S and the SNCA variants rs5019538 and rs356182, were less frequent in PD + RBD compared to PD-RBD. The gene discussed is LRRK2; the disease is Parkinson disease.