LRRK2 and Parkinson disease: Two were variants in the SNCA locus, which were not on LD with the primary SNCA variant rs10005233-T variant nor with each other, whose minor alleles were associated with decreased risk for PD + RBD (rs5019538-G, OR = 0.85, 95% CI = 0.81–0.89, p = 2.46E−10 and rs356182-G, OR = 0.89, 95% CI = 0.84–0.95, p = 0.0001), and one was the LRRK2 p.G2019S variant, also associated with a reduced risk for PD + RBD (rs34637584, OR = 0.41, 95% CI = 0.28–0.61, p = 1.04E−5, the carrier frequency for this variant across the different cohorts is detailed in Table 3).