A recent longitudinal single-cell RNAseq study of HGSOC in patients following neoadjuvant chemotherapy identified 12 tumour cell clusters including a cluster showing subclonal enrichment of a “stress-associated” gene signature comprising EMT regulators, stemness, pro-survival genes, and NF-κB targets (481 genes in total) [38]. The gene discussed is NFKB1; the disease is neoplasm.